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    Connectors for Media and Buffers

    Getting It Right

    Accurate preparation of media and buffers is critical to the biomanufacturing process. Obtaining the correct mixtures of media and media supplements, buffers and buffer solutions, salts and other process chemicals are key components in successfully producing biopharmaceutical products. Formulating these essential media and buffer mixtures makes use of large volumes of raw materials, which requires flexible, cost-efficient workflow designs that ensure on-time delivery to meet market demands. 

    Learn how single-use systems are to aid sampling

    Name of the Game: Overall Manufacturing Performance

    Media and buffers determine the concentration of the target protein in the fermentation broth and optimization of cell culture conditions for successful biologic production. Growing demand for media and buffer volumes and faster prep times, including increase in titers and continuous processing, means manufacturers are implementing single-use technologies to improve manufacturing efficiency and productivity during media and buffer preparation. 

    Innovative New Media and Buffers Technologies to Streamline Production

    • Single-use systems
    • Continuous biomanufacturing
    • In-line dilution or conditioning systems
    • Single-use powder and liquid formulations
    • Pre-weighed, ready-to-dispense packaging systems
    • Smaller scale bioreactors
    • High-performance, complex culture media and buffers
    • Increased use of process analytics
    • Ready-to-use diluted buffers and buffer concentrates
    Innovative New Media and Buffers Technologies to Streamline Production

    Media Transfer Innovation and Dedication

    CPC’s team of dedicated engineers are focused on providing safe and fast fluid transfer in media and buffer preparation and usage for both traditional batch manufacturing and single-use systems. This ongoing focus offers you the widest selection of media transfer products―including sterile connects, sterile disconnect, quick connects and more―to meet your media and buffers workflow requirements. By collaborating with your bioprocessing engineers and research scientists, we use our expertise and experience to help define, design and implement the media transfer systems needed to ensure flexible, robust upstream and downstream processes for your manufacturing operations. 

    CPC Aseptic Connectors and Disconnect Benefits

    • Simple and secure connections and disconnections
    • Easy integration of single-use components including XX, YY
    • Prevention of contamination, such as bacteria, and environmental contaminants like dust and dirt, to protect end product
    • Connection of single-use components in a non-sterile environment to maintain media sterility
    • Secure, tool-free flow path disconnections
    • Rapid transfer of high volumes of buffer and media
    • Sterile connections between presterilized single-use systems and stainless-steel bioreactors for aseptic media transfer

    CPC Aseptic Connectors Provide Safe, Fast Media Transfer

    CPC aseptic connectors are the answer whenever you need to connect or disconnect two separate fluid paths with sterility assurance, even in non-sterile environments. No matter the environment, CPC bioprocessing connectors provide sterile media transfer during the preparation and distribution of media and buffers, making the mixtures available when and where they are needed.

    Multipurpose Flexibility

    CPC sterile connectors provide flexibility for biopharmaceutical manufacturers to easily combine multiple components, single-use, batch or hybrid systems including process containers, tubing manifolds, transfer lines, bioreactors and other bioprocess equipment. When changeovers need to occur, CPC genderless connectors make it easy to connect components and processes. Multiple termination options meet today’s mounting and flow requirements.

    Innovative Design

    Our team of bioprocessing design and application engineers develop innovative, high-quality products that make sterile media transfer safe and easy. Because media and buffer configurations vary as much as the connectors and filters, options for tubing, CPC sterile connectors and disconnects come in an expanding variety of sizes, configurations, termination options and materials. The innovative Flip-Click-Pull connection process ensures ease of use and connection assurance.

    Trusted Reliability

    CPC sterile connectors are purpose-built for bioprocessing applications from upstream fermentation to downstream freeze-thaw―and everything in-between. By helping maintain aseptic transfer of media, CPC sterile connectors facilitate getting the best yields at a cost-efficient price. All CPC bioprocessing connection solutions are rigorously tested ─ including materials testing, product testing and torture testing to failure ─ to meet product specifications. As a matter of fact, CPC offers reliable, reproducible performance and provides validation and extractable reports that support the performance attributes.

    Overall Robustness

    Built to manage the media transfer requirements of media and buffer preparation, CPC sterile connectors deliver optimized flowrates with excellent flow to size ratio for superior performance. CPC purpose-built bioprocessing connectors are precision engineered to be compatible with a wide variety of media and buffer components, chemicals, and systems. We provide a unique combination of industry expertise with the broadest portfolio of products including sterile connects, sterile disconnects, SIP connections and quick connects.

    Sterility Assurance

    Increased volume and product diversity is driving manufacturers to design their facilities for shorter production runs with multiple changeovers. Single-use bags and transfer lines use CPC MPC or MPX Connections and SaniQuik™ Adaptors for quick changeovers. Robust and easy-to-use single-use connectors from CPC maintain flow path sterility and integrity while enabling biopharmaceutical manufacturers to improve production yields, decrease time-to-market and reduce costs.

    Assurance of Supply

    CPC has a proven track record of providing products consistently under their original specifications and quality requirements through having a strong supply assurance plan. The plan includes control of the manufacturing process from raw materials to final product manufacturing. Biopharma customers have confidence in CPC to deliver critical products acquired by a track record of accurate lead times, identifying and communicating potential delays and, most importantly, by sound supply chain management.

    Read how single-use components advance the flexibility over stainless steal equipment use

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    Download Product Validation Reports
    Sterile Connectors

    Easy-to-use AseptiQuik® and MicroCNX® Connectors provide quick and sterile connections, even in non-sterile environments—a critical capability for your biopharmaceutical manufacturing.

    Sterile Disconnectors

    With an easy push of the connector thumb latch, our sterile disconnectors maintain sterility on both sides of the system during disconnection.

    Sterile Combination Connectors

    Be assured of both a sterile connect and sterile disconnect with our all-in-one, single-use AseptiQuik® DC connection technology.

    Open Format Connectors

    Transfer media quickly and easily between single-use bag systems, tube sets and stainless process equipment.

    From CPC's Knowledge Center

    Bridging the Connectivity Gap Between Traditional Sensors and Single-Use Systems

    Find out how secure, leak-free connection of traditional sensors to single-use assemblies is paramount in ensuring the accuracy of measurements taken and protection of the manufacture of expensive drug products.

    How Single Use Connectors Advance Aseptic Processing

    Today’s market demand on biologic and pharmaceutical manufacturers to develop new drugs — combined with the economic environment — is challenging bioprocesses to review their processing systems and seek ways to make them more flexible, reliable and cost effective.

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